SLAY THE SPIRE 2 · EARLY ACCESS

The Ultimate STS2 Strategy Guide

Best builds for all 5 characters · Card tier lists · Relic database · Beginner walkthrough · Boss strategies · Co-op synergy guide

5

Characters

567

Cards

286

Relics

30+

Guides

📖 Beginner's Guide 🦸 Pick Your Character 🏆 Best Builds 📊 Card Tier List 💎 All Guides 💀 New: Necrobinder

Characters

3 returning classics + 2 brand-new heroes. Every character supports multiple viable archetypes.

Ironclad

Strength · Block · Exhaust

Strength Block Engine Self-Damage Exhaust

Silent

Poison · Shiv · Discard

Poison Shiv Spam Discard

Defect

Orbs · Powers · Zero-Cost

Orb Spam Power Scaling 0-Cost Spam

Necrobinder

Summon · Sacrifice · Soul

Summon Army Sacrifice Soul Engine

Regent

Command · Sly · Star

Command Sly Control Star Scaling

Latest Guides

Updated daily — covering every character, mechanic, and ascension strategy.

Slay the Spire 2 Beginner Guide: From First Run to Consistent Wins

🕐 May 20 👁 12,845 views 💬 89 comments

Ironclad Strength Build: One-Shot Bosses with Demon Form + Limit Break

🕐 May 19 👁 9,231 views 💬 67 comments

→ 2 Tier List

Complete Card Tier List: S~D Rankings for All 5 Characters (May 2026)

🕐 May 18 👁 8,720 views 💬 54 comments

Silent Poison Build Guide: Stack 999 Poison with Catalyst + Burst

🕐 May 17 👁 7,456 views 💬 43 comments

Necrobinder Summon Build: Flood the Spire with Skeleton Army

🕐 May 16 👁 6,892 views 💬 38 comments

S-Tier Relics Breakdown: Which Ancient Relics You Should Always Take

🕐 May 15 👁 5,987 views 💬 31 comments

Defect Power Scaling Build: 100+ Damage Per Turn with Echo Form

🕐 May 14 👁 5,321 views 💬 28 comments

Best Duo Synergies: Necrobinder + Ironclad Chemistry Explained

🕐 May 13 👁 4,876 views 💬 24 comments

Act 3 Corrupted Heart Boss Guide: Mechanics & Strategy Per Character

🕐 May 12 👁 4,210 views 💬 19 comments

Regent Command Build: Mastering the "Sly" Mechanic for Precision Control

🕐 May 11 👁 3,945 views 💬 16 comments